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Clinical Trials/NCT00599599
NCT00599599
Unknown
Not Applicable

Pilot Intervention for PTSD, Nonadherence, and HIV Risk

Kent State University2 sites in 1 country70 target enrollmentApril 2005

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Stress Disorders, Post-Traumatic
Sponsor
Kent State University
Enrollment
70
Locations
2
Primary Endpoint
PTSD symptoms
Last Updated
17 years ago

Overview

Brief Summary

The primary aim of this project is to examine the efficacy of prolonged exposure (PE) therapy at reducing HIV-related PTSD symptoms, increasing adherence to antiretroviral medication regimens, and increasing health-related quality of life (QOL) in HIV+ patients.

Detailed Description

HIV+ patients will be randomized to receive either PE therapy (up to 18 possible sessions) or weekly symptom monitoring (described below) and will complete measures of PTSD, adherence, and QOL pre- and post-intervention and at 3- and 6-month follow-up assessments. Secondary analyses will examine the impact of the intervention on disorders commonly comorbid with PTSD (i.e., anxiety, mood, and substance abuse/dependence disorders).

Registry
clinicaltrials.gov
Start Date
April 2005
End Date
February 2010
Last Updated
17 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Eligibility Criteria

Inclusion Criteria

  • Must be HIV+
  • Must meet PTSD diagnostic criteria
  • Must be taking HIV medications
  • Must be able to read and write in English

Exclusion Criteria

  • Current or previous diagnosis of schizophrenia, any current diagnosis with psychotic features, or current suicidal ideation
  • Being in a current abusive relationship or ongoing intimate relationship with one's assailant
  • Mental retardation

Outcomes

Primary Outcomes

PTSD symptoms

Time Frame: pre- & post-intervention, 3-month post, & 6-month post

Secondary Outcomes

  • Adherence to HIV medications(pre- & post-intervention, 3-month post, & 6-month post)
  • Health-related Quality of Life(pre- & post-intervention, 3-month post, & 6-month post)

Study Sites (2)

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