Effect of Repetitive Transcranial Magnetic Stimulation in Patients With Peripheral Vestibular Dysfunction

Not Applicable

Completed

• Conditions: Peripheral Vestibular Dysfunction
• Interventions: Device: Repetitive transcranial magnetic stimulation; Other: Cawthorne Cooksey exercises

• Registration Number: NCT05613634
• Lead Sponsor: October 6 University

Brief Summary

Background: Vestibular dysfunctions are common disorders in the adult population that can develop at any life decade. Most of the patients with vestibular dysfunction suffer from balance disorders and vertigo that may have a negative impact on daily living activities and social participation.

Objectives: To investigate the effect of repetitive transcranial magnetic stimulation added to vestibular physical therapy exercises on functional recovery in patients with vestibular dysfunction.

Hypothesis: There is no effect of repetitive transcranial magnetic stimulation added to vestibular physical therapy exercises on functional recovery in patients with vestibular dysfunction.

Detailed Description

Not available

Study Timeline

• Study Start: 2022-05-10
• Primary Completion: 2022-08-10
• Study Completion: 2022-10-10
• Status Verified: 2022-11
• Study First Submitted: 2022-11-06
• Study First Submitted QC: 2022-11-06
• Last Update Submitted: 2022-11-06
• Study First Posted: 2022-11-14
• Last Update Posted: 2022-11-14

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 35

Inclusion Criteria

• patients diagnosed by an audiologist with a chronic uncompensated unilateral peripheral vestibular weakness
• age ranged from 30 to 60 years, and duration of illness ranged from 4 to 32 months

Exclusion Criteria

• benign paroxysmal positional vertigo
• bilateral peripheral vestibular weakness
• central vestibular disorders
• acute vestibular weakness
• vertigo of vascular origin (Vertebrobasilar insufficiency) or cervical origin

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: FACTORIAL

Arm && Interventions

Group	Intervention	Description
Study group	Repetitive transcranial magnetic stimulation	The study group received rTMS in addition to the vestibular physical therapy exercises
Study group	Cawthorne Cooksey exercises	The study group received rTMS in addition to the vestibular physical therapy exercises
Control group	Cawthorne Cooksey exercises	Patients in control group received the vestibular physical therapy exercises, three sessions a week for four weeks

Primary Outcome Measures

Name	Time	Method
Video-nystagmography (VNG)	35 minutes	The VNG was used to assess unilateral vestibular canal weakness. It was used with caloric testing to analyze eye movements using video imaging technology, in which hi-tech video goggles with infrared cameras were used

Secondary Outcome Measures

Name	Time	Method
Dizziness handicap inventory (DHI)	20 minutes	is used in clinical work and in research to assess the impact of dizziness on QoL. The self-report questionnaire was designed to quantify the handicapping effect of dizziness imposed by vestibular system disease. The Arabic version of the DHI has good validity and reliability for assessing patients' self-perception of the handicap and its impact on their QoL

Trial Locations

Locations (1)

October 6 University; 🇪🇬 Giza, Egypt