Vector Analysis of Body Composition in Hospitalized Cirrhotic Patients

• Conditions: Infection

• Registration Number: NCT02017301
• Lead Sponsor: Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran

Brief Summary

Patients with acute decompensation of cirrhosis, or acute on chronic liver failure often present with malnutrition, and due to the in-hospital stay, their nutritional intake can vary widely, with several periods of fasting, and sometimes insufficient nutritional support. Therefore patients are prone to develop malnutrition or, the already present malnutrition worsens its status.

Our aim is to evaluate the daily changes in nutritional status in patients with acute decompensation of cirrhosis and evaluate the changes in plasma and serum biomarkers.

Detailed Description

Not available

Study Timeline

• Study Start: 2012-11
• Study First Submitted: 2012-12-06
• Study First Submitted QC: 2013-12-16
• Study First Posted: 2013-12-20
• Status Verified: 2019-01
• Last Update Submitted: 2019-01-30
• Last Update Posted: 2019-02-01
• Primary Completion: 2020-04
• Study Completion: 2021-04

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 79

Inclusion Criteria

• Age 18-75 years old
• Patients with confirmed cirrhosis.
• Any etiology
• Hospitalized with acute decompensation of cirrhosis
• Signed informed consent

Exclusion Criteria

• Pregnancy
• Amputation
• Incomplete data

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Changes in nutritional status	Daily measurement up to 30 days	Nutritional status will be measured with bioelectrical impedance analysis (Vector and phase angle)

Secondary Outcome Measures

Name	Time	Method
Evaluation of inflammatory cytokines	Samples will be collected at the baseline evaluation.	ELISA's test

Trial Locations

Locations (1)

Instituto Nacional de Ciencias Medicas y Nutrición Salvador Zubiran; 🇲🇽 Mexico, D.F, Mexico