Comparison of long-term effects on knee joint function between selective cox-2 inhibitor and naproxen + esomeprazole combination regimen after arthroscopic meniscus operatio
- Conditions
- Diseases of the musculoskeletal system and connective tissue
- Registration Number
- KCT0003790
- Brief Summary
In patients undergoing arthroscopic meniscus surgery, it was confirmed that pain and function improved after operative treatment, and it can be concluded that the selective COX-2 inhibitor and naproxen + esomeprazole combination therapy contributed to adequate pain control in both patient groups. There was no statistical difference between the two groups, and oral drug administration after operation has clinical significance in pain control and effective functional improvement
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 46
1) Patients undergoing arthroscopic meniscus operation for meniscus injury
2) Adult patients aged 19 to 54 years
3) Patients with Kellgren-Lawrence grade II or less
4) Patients who pre-agreed to the study
5) Patients with a VAS score of 5 or more
1) Patients undergoing surgery for other associated injuries other than meniscus in the affected knee
2) Patients with cartilage damage with Outerbridge grade III or IV
3) Patients with a history of allergy to NSAIDs
4) Patients with a mental disorder and are in cure
5) Patients with abnormal findings on hepatic function test, renal function test, hemoglobin level, etc. who can not take NSAIDs
Study & Design
- Study Type
- Interventional Study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method IKDC subjective score;Lysholm knee score;VAS pain score
- Secondary Outcome Measures
Name Time Method