The emotional response in Parkinson`s disease before and after bilateral STN stimulatio
- Conditions
- Parkinson movementdisorder10028037
- Registration Number
- NL-OMON30351
- Lead Sponsor
- Academisch Medisch Centrum
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- Not specified
- Target Recruitment
- 10
Inclusion Criteria
- disease duration et least 5 years or more
- experimental condition: patiënts who undergo an STN stimulation
Exclusion Criteria
- dementia (Mattis DRS < 120)
- other serious central nervous system diseases or other diseases.
Study & Design
- Study Type
- Observational non invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>auditive startle reflex (latency, duration and peak of the amplitude EMG<br /><br>activity per muscle)<br /><br><br /><br>tactile startle reflex (latency, duration and peak of the amplitude EMG<br /><br>activity per muscle)<br /><br><br /><br>Psychogalvanic respons (difference between the minimum and maximum activity in<br /><br>a period of four seconds after stimulus onset)<br /><br><br /><br>Affective reports on arousal and valence (Self Assessment Manikin)</p><br>
- Secondary Outcome Measures
Name Time Method <p>General cognitive functioning (Mattis DRS)<br /><br>Executive functions (letterfluency, Trail Making Test en Stroop)<br /><br>Depression and/or anxiety (HADS)<br /><br>Mood states (PANAS/POMS)<br /><br>Motor symptoms (UPDRS part 3)</p><br>