Prevention of postoperative sore throat

Phase 4

Recruiting

• Conditions: Post operative sore throat; post operative sore throat; budesonide; EMLA

• Registration Number: TCTR20230907006
• Lead Sponsor: Department of Anaesthesia,Batra Hospital & Medical Research Centre, New Delhi, India

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2023-09-07
• Last Update Posted: 19 August 2024
• Study Completion: 2024-11-19

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 162

Inclusion Criteria

1.Age 18-65 years.

2.ASA physical status I and II.

3.Patients undergoing elective surgeries requiring endotracheal intubation

Exclusion Criteria

1.Anticipated difficult airway.
2.Requiring more than 2 intubation attempts.
3.Known allergy to local anaesthetic drug.
4.Recent history of steroid or non-steroidal anti-inflammatory drug use
5.Systemic illness with presenting complaints of sore/dry throat (diabetics with polydipsia, hypertensives on diuretics, moribund bed ridden patients).
6.History of airway related morbidity (post operative sore throat [POST])
7.Patients undergoing head and neck, intraoral/nasal surgery, or recent history of such surgery.
8.Surgery in prone position
9.Ongoing upper and lower respiratory tract inflammation/infection.
10.Patients requiring post operative mechanical ventilation.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Post operative sore throat (POST) At 2 hours, 6 hours, and 24 hours postoperatively Assessed using a 4-point scale: '0' no sore throat to '3' severe sore throat.

Secondary Outcome Measures

Name	Time	Method
Post operative cough At 2 hours, 6 hours, and 24 hours postoperatively Assessed using a 4-point scale: '0' no cough to '3' severe cough. ,Post operative Hoarseness At 2 hours, 6 hours, and 24 hours postoperatively Assessed using a 4-point scale: '0' mild hoarseness to '4' severe hoarseness.,Peri-intubation haemodynamics From 5- minutes prior to induction of anaesthesia till 5-minutes post intubation of trachea heart rate (beats per minute), systolic blood pressure (mmHg), diastolic blood pressure (mmHg), and mean arterial pressure (mmHg) will be measured