The Effect of Spermatic Vein Embolization on Prostatic Hypertrophy
- Conditions
- Varicocele
- Registration Number
- NCT00639899
- Lead Sponsor
- Maaynei Hayesha Medical Center
- Brief Summary
In varicocele the venous pressure in the prostatic bed is increased .This may result in raised hydrostatic pressure which in turn may stimulate prostatic hypertrophy.
Restoring normal venous drainage is expected to lower hydrostatic pressure followed by inhibition of prostatic growth and possibly leading regression in prostatic dimensions.
- Detailed Description
35 male patients, aged 45 years or older, with documented benign prostatic hypertrophy (BPH)and varicocele as visualized by ultrasound and/or termography examination will be enrolled.
Each patient will undergo a full urologic examination to exclude possible malignancy as well as a thorough medical examination to establish eligibility for treatment.
In all selected patients the varicocele will be obliterated by means of embolization of the spermatic veins.
The patients will be followed every three months by abdominal ultrasound as well as by serial PSA for a period of 6-12 months.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- Male
- Target Recruitment
- 35
- Male
- Age > 45 < 80 years
- BPH
- Bilateral varicocele.
- Coagulation disturbance
- CHF
- Malignancy
- Renal failure.
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- SINGLE_GROUP
- Primary Outcome Measures
Name Time Method Safety performance of the procedure. Reduction of above 20% in prostatic calculated volume. 1 year
- Secondary Outcome Measures
Name Time Method Reduction of above 20% in nocturia 1 year
Trial Locations
- Locations (1)
Maaynei Hayeshua Medical Center
🇮🇱Bnei Brak, Israel