VALUE OF RADIONUCLIDE CISTERNOGRAPHY IN PATIENTS WITH CEREBROSPINAL FLUID LEAK
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 113
- 主要终点
- RC /SPECT/CT imaging
研究概览
简要总结
Radionuclide cisternography (RC) is a nuclear medicine examination based on intrathecal injection of [111In]diethylenetriaminepentaacetic acid ([111In]DTPA). It is prescribed for two recommendations: detection of cerebrospinal fluid (CSF) leak/fistula and diagnosis of normal pressure hydrocephalus.
In the search part of CSF leak/fistula, RC offers the benefit of a 24-hour study of CSF unlike other reference tests.
In addition to SPECT/CT imaging, the radiopharmacist performs sampling in nasal cavities and throat of the patient to collect a possible flow of CSF.
These samples are analysed by radioactivity measurements and bring an added value to the exam.
The interest of this examination for management of CSF leak/fistula remains unclear.
The aim of this study is to identify and analyse results of all RC examinations performed since 2005 in the Nuclear Medicine department of the Neurological Hospital.
The full analysis of patients will allow discussing the role of RC in management of CSF leak/fistulae in clinical practice.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •patients who received a convocation for realization of RC (extraction with GERA, software of Nuclear Medicine)
排除标准
- •patients who received a convocation for realization of RC with "valve" protocol
结局指标
主要结局
RC /SPECT/CT imaging
时间窗: one week
Results of RC including results of SPECT/CT imaging and results of swabs counting (nasal cavities and throat or ear if applicable)
次要结局
未报告次要终点