Performance of the Hypotension Prediction Index With Invasive Arterial Pressure Waveform in Liver Transplantation
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 60
- 试验地点
- 2
- 主要终点
- Accurate hypotension prediction of EV1000 system
研究概览
简要总结
A prospective, open-label and single-center study to determine whether the use of Acumen Hypotension Prediction Index software predicts the occurrence of hypotension.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Diagnostic
- 盲法
- None
入排标准
- 年龄范围
- 20 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Written informed consent
- •Age ≥ 20 years;
- •Scheduled liver transplantation
- •Planned pressure monitoring with an arterial line;
- •General anesthesia
排除标准
- •Contraindication for invasive blood pressure monitoring
- •End-staged renal disease
- •pre-operative MAP <65 mmHg
- •Severe heart failure
- •Severe cardiac shunt
- •Severe aortic stenosis
- •Severe atrial fibrillation
结局指标
主要结局
Accurate hypotension prediction of EV1000 system
时间窗: MAP measurements of each case were recorded every 20 s by the EV1000 system from induction to the end of surgery, assessed up to 1 day.
Analyze the actual incidence of hypotension after HPI alarm more than 85 within 15 min
Severity of intraoperative hypotension
时间窗: MAP measurements of each case were recorded every 20 s by the EV1000 system from induction to the end of surgery, assessed up to 1 day
MAP measurements were recorded every 20 s by the EV1000 system from induction to Time-weighted average mean arterial pressure (TWA-MAP) \< 65 mmHg
Incidence of intraoperative hypotension
时间窗: MAP measurements of each case were recorded every 20 s by the EV1000 system from induction to the end of surgery, assessed up to 1 day
Frequency, duration of intraoperative hypotension, which defined as MAP \< 65 mmHg at least 1 min
次要结局
- Hospital stay and ICU stay(Days from admission to discharge, assessed up to 1 month)
- Adverse effects(Days from admission to discharge, assessed up to 1 month)
- Mortality after surgery(Days from admission to discharge, assessed up to 1 month)