Pregnancy and the human brain: a window of neuroplasticity
Recruiting
- Conditions
- the effects of a healthy pregnancyn.v.t.
- Registration Number
- NL-OMON51565
- Lead Sponsor
- Amsterdam UMC
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Not specified
- Target Recruitment
- 250
Inclusion Criteria
1. Women of age between 20 and 45 years
2. The intention to become pregnant (pregnancy group) or not (control group) in
the near future
3. No neurological disorder/disease
4. No contraindications to MRI
5. No previous pregnancy beyond the first trimester
Exclusion Criteria
1. History of neurological disorder/disease
2. Contraindications to MRI, which include metal implants, heart arrhythmia,
claustrophobia, and possible early pregnancy
3. A previous pregnancy beyond the first trimester
Study & Design
- Study Type
- Observational invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>Changes in measures of brain structure and function relative to the<br /><br>pre-pregnancy baseline session. </p><br>
- Secondary Outcome Measures
Name Time Method <p>We will relate these changes in brain structure and function during pregnancy<br /><br>to gestational hormone levels, genetic factors, biological and lifestyle<br /><br>factors, contingent changes in cognitive and social-cognitive functioning and<br /><br>behavioral and neural indices of postpartum maternal responsiveness.</p><br>