Reconstructive surgical therapy of peri-implantitis-related bone defects: Application of a bovine-derived bone xenograft with or without a resorbable collagen membrane. Multicenter controlled randomized clinical trial

Periocentrum Bilbao0 sites43 target enrollmentJune 3, 2019

Overview

2023 Results article in https://pubmed.ncbi.nlm.nih.gov/36802084/ (added 17/03/2023)

Registry

who.int

Start Date

June 3, 2019

End Date

February 28, 2022

Last Updated

3 years ago

Study Type

Interventional

Sex

All

Sponsor

Periocentrum Bilbao

•1\. Show radiographically peri\-implant intraosseous defects of at least 3mm depth.
•2\. Depth of clinical probing \= 5mm with bleeding and/or suppuration.
•3\. Intra\-surgically, the infra\-osseous defect must have at least one intraosseous component of 3mm and a width of no more than 4mm.
•4\. The implant to be treated must have been in function for at least 12 months.

•1\. Has diabetes mellitus, hyperparathyroidism and/or osteomalacia.
•2\. Treated with corticosteroids.
•3\. Medicated with drugs that induce gingival hyperplasia.
•4\. Allergic to penicillin or who have taken antibiotics in the last 6 months.
•5\. Pregnant or breast\-feeding patients.
•6\. Patients with osteoporosis.
•7\. Impossibility of stabilizing bovine bone with collagen or primary closure of soft tissue.
•8\. Patients with collagen allergy.
•9\. Patients treated with radiotherapy.