MedPath

Quercus Robur in Reducing the Craving for Alcohol.

Phase 2/3
Recruiting
Conditions
Alcohol dependence,
Registration Number
CTRI/2023/10/059212
Lead Sponsor
National Homoeopathy Research Institute in Mental Health, Kottayam.
Brief Summary

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|**Title**

**A Pilot, Double-Blinded, Randomized Controlled Trial to Assess the Effectiveness of Quercus Robur Glandium Spiritus Vs Individualized Homoeopathic Medicine in Reducing the Craving for Alcohol.**

|**Short title**

Quercus Robur in Alcohol Dependence- A pilot study.

|**Protocol number**

2.4

|**Study design**

Two-armed, Parallel Group Randomized Controlled Trial.

|**Study duration**

6 months (Pre-trial preparations-1 month+ 2months for enrolment +2 months for follow up+ 1 month for compilation)

|**Study centre(s)**

Regional Research Institute(H), Hyderabad

|**Objective (s)**

To assess the effectiveness of Quercus Robur Glandium Spiritus compared to Individualized Homoeopathy in reducing the Craving for alcohol in Alcohol Dependence Syndrome patients.

    

|**Number of subjects**

30 subjects (15 for each arm) would be selected from OPD and IPD of NHRIMH, Kottayam.

|**Diagnosis and main inclusion criteria**

Diagnosis shall be made according to ICD-10 criteria.

Subjects of ages 18 to 60 years from various occupations and socio-economic conditions suffering from ADS, willing to quit alcohol.

|**Study product, Dose, regimen**

Dynamic medicinal preparation of Quercus robur and Individualized Homoeopathic medicine in centesimal scale will be given as per the principles of Homoeopathy shall be administered orally in pills form

 

|**Statistical methodology**

Student’s *t*-test, and any other appropriate statistical tests as applicable by using SPSS software, version-20.0/ Statscraft software

|**Proposed tools/ scales for the study**

Screening-AUDIT, CIWA-Ar; Severity assessment-SADQ, PACS

Detailed Description

Not available

Recruitment & Eligibility

Status
Open to Recruitment
Sex
All
Target Recruitment
30
Inclusion Criteria
  • Fulfilling ICD-10 diagnostic criteria for Alcohol dependence 2.
  • Patients willing to quit alcohol 3.
  • Written informed consent.
Exclusion Criteria

1.Patients with severe systemic illness 2.Cases with other substance abuse 3.With co-morbid severe psychiatric illness 4.Patients who had previously suffered severe withdrawal symptoms 5.Pregnant women and lactating mothers.

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Penn Alcohol craving Scale (PACS)0,1,2,3,4,8 weeks
Secondary Outcome Measures
NameTimeMethod
Severity of Alcohol Dependence Scale-SADQ0,1,2 MONTHS

Trial Locations

Locations (1)

Regional Research Institute (H), Hyderabad

🇮🇳

Hyderabad, TELANGANA, India

Regional Research Institute (H), Hyderabad
🇮🇳Hyderabad, TELANGANA, India
Dr Deepthi Gilla
Principal investigator
8111990221
drdeepthigilla@gmail.com

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