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Clinical Trials/NCT02214576
NCT02214576
Completed
N/A

Observational Study of High Flow Nasal Canula Oxygen to Preoxygenate ARDS Patients That Require Intubation

Hôpital Louis Mourier1 site in 1 country50 target enrollmentSeptember 2011

Overview

Phase
N/A
Intervention
Not specified
Conditions
Acute Respiratory Distress Syndrome
Sponsor
Hôpital Louis Mourier
Enrollment
50
Locations
1
Primary Endpoint
Oxygen saturation
Status
Completed
Last Updated
10 years ago

Overview

Brief Summary

Tracheal intubation in the ICU is associated with significant complications and morbidity. Desaturation is among the most frequent and hazardous complication, occurring in almost one out of four intubations, that may in some instances lead to cardiac arrest; despite appropriate preoxygenation. Non-invasive ventilation may help improve preoxygenation but does not allow for apneic oxygenation and may not be performed in patients with neurological impairment. High flow nasal canula oxygen is increasingly used in the ICU in patients with acute hypoxemic respiratory failure and may be used to improve preoxygenation. It is currently used in our ICU for that purpose. Because high flow nasal canula oxygen is our first line oxyten therapy for patients with acute respirtory distress syndrome, we sought to determine its use as a means to ensure preoxygenation in those ARDS patients that require intubation.

Detailed Description

High flow nasal canula oxygen is increasingly used to provide heated and humidified oxygen in patients with acute respiratory failure. One of the major advantages of high flow nasal canula oxygen is the possibility to maintain oxygenation during laryngoscopy and thereby providing high flow apneic oxygenation. In addition, and contrary no non-invasive ventilation, preoxygenation may be used in patients with neurological impairment. Finally, the interest of this device is that it is the same that is maintained throughout the whole management of the patient, from ICU admission to intubation.

Registry
clinicaltrials.gov
Start Date
September 2011
End Date
August 2015
Last Updated
10 years ago
Study Type
Observational
Sex
All

Investigators

Sponsor
Hôpital Louis Mourier
Responsible Party
Principal Investigator
Principal Investigator

Prof Jean-Damien RICARD

Professor of Intensive Care Medicine, Assistant-head of ICU

Hôpital Louis Mourier

Eligibility Criteria

Inclusion Criteria

  • ARDS according to the Berlin criteria
  • use of high flow nasal canula oxygen

Exclusion Criteria

  • Not provided

Outcomes

Primary Outcomes

Oxygen saturation

Time Frame: 30 minutes

oxygen saturation measured by pulse oxymetry during intubation and compared to levels before intubation

Secondary Outcomes

  • complications(60 minutes)

Study Sites (1)

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