Randomized crossover trial comparing memantine or amantadine for Parkinson's disease with motor fluctuations in Juntendo
Not Applicable
- Conditions
- Parkinson's disease
- Registration Number
- JPRN-UMIN000010596
- Lead Sponsor
- Department of Neurology, Juntendo University School of Medicine
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- Male
- Target Recruitment
- 40
Inclusion Criteria
Not provided
Exclusion Criteria
1)Patient has been administered amantadine or memantine already. 2)Patient dose needs to be changed during the study period cholinesterase inhibitors. 3)Patients scheduled to come into effect during the study period deep brain stimulation surgery(DBS). 4)Women and lactating women might be pregnant, are pregnant. 5)In addition, patients attending physician was deemed inappropriate.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Improvement of dyskinesias
- Secondary Outcome Measures
Name Time Method Changes in cognitive function score Changes in REM sleep behavior disorder