Comprehensive Cardiac Rehabilitation Feasibility After Stroke

Not Applicable

Completed

Brief Summary: Comprehensive Cardiovascular Rehabilitation Feasibility After Stroke (CCR FAST) will evaluate the feasibility of enrolling Regions Hospital stroke patients in a Comprehensive Cardiovascular Rehabilitation (CCR) program. CCR will include aerobic exercise and patient education (regarding risk factors and medication compliance), similar to the rehabilitation program for cardiac disease patients. The overall goal of CCR FAST is to demonstrate the feasibility and safety of including stroke patients in a CCR program, while examining the clinical value in reducing stroke recurrence, myocardial infarction, readmission, and mortality in stroke patients.

Recruitment & Eligibility

Inclusion Criteria

Age ≥ 18 years
Patient has suffered an ischemic stroke
Patient should be ambulatory (non-disabling stroke) to be able to participate in the CCR exercise program
Patient is able to start cardiac rehabilitation within 2 weeks of stroke

Exclusion Criteria

No baseline (index admission for ischemic stroke) MRI completed
Life expectancy < 1-year
Presence of brain hemorrhage: intracerebral hemorrhage, subarachnoid hemorrhage, subdural hematoma, or epidural hematoma
Concurrent diagnosis of seizure disorder
Patient with moderate or severe neurologic deficits, limiting their ability to participate in the CCR exercise program
Cardiopulmonary conditions preventing the patient from participation, such as severe heart failure, severe aortic stenosis, and exercise-induced asthma
Patient with cognitive dysfunction impairing their ability to follow directions
Anticipated procedures such as carotid stenting, carotid endarterectomy, and intracranial aneurysm coiling
Patient unable to commit to the frequent visits of the CCR program
Participation in other interventional research (observational research is allowed)
Unable to have brain MRI
Non-English speaker
Pregnant women

Arm && Interventions

Group	Intervention	Description
Intervention	Exercise	Exercise intervention

Primary Outcome Measures

Name	Time	Method
Attendance Rate	12 weeks	75% attendance at comprehensive cardiovascular rehabilitation (CCR) sessions

Secondary Outcome Measures

Name	Time	Method
Hospital Readmission	6 month	rate, for a cardiovascular or cerebrovascular indication
Number of Participants With or Without Silent Stroke	6 month	rate, on MRI
Number of Patients With or Without Recurrent Stroke	6 month	Recurrent stroke in follow-up period
Number of Participants With or Without Myocardial Infarction	6 month	Myocardial infarction in follow-up time
Number of Participants Without Death	6 month	rate

Locations (3): Regions Hospital
🇺🇸
Saint Paul, Minnesota, United States
Regions Hospital Outpatient Cardiopulmonary Rehabilitation Clinic
🇺🇸
Saint Paul, Minnesota, United States
HealthPartners Neuroscience Center
🇺🇸
Saint Paul, Minnesota, United States