Effect of Local Injection of Umbilical Cord Blood Derived Serum versus Local Injection of Platelet Rich Plasma in the Treatment of Striae Distensae

Phase 1

Recruiting

Conditions: Striae Distensae.

Registration Number: IRCT20221130056672N2

Lead Sponsor: Tehran University of Medical Sciences

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Recruiting

Sex: All

Target Recruitment: 30

Inclusion Criteria

Age between 18 and 50 years
Full satisfaction of the participant in the plan
Has striae alba (with all three degrees of mild, moderate, severe)

Exclusion Criteria

Inflammatory acne
Active herpes labialis
Local infections in the treatment area
Prone to keloid
Malignancy
Pregnancy
Breastfeeding
Use of drugs that can affect bleeding or clotting mechanism
Immunosuppression
Use of local and systemic steroids
Disease systemic diseases (such as high blood pressure ,Diabetes ,heart, kidney and liver diseases)
The use of exfoliators 4 weeks before treatment
In places where botulinum injection has been done, should not be done due to the possibility of microneedle toxin release.

Study & Design

Study Type: interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Epidermis and dermis thickness. Timepoint: Before the start of the intervention and two months after the end of the treatment period (Four months after the start of the treatment). Method of measurement: Skin Scanner.;The amount of collagen formation. Timepoint: Before the start of the intervention and two months after the end of the treatment period (Four months after the start of the treatment). Method of measurement: Visoface.

Secondary Outcome Measures

Name	Time	Method
Safety. Timepoint: At the beginning of the intervention, at each re-visit session and two months after the end of the treatment period (four months after the start of the treatment). Method of measurement: Patient history.;Effectiveness. Timepoint: At the beginning of the intervention, at each re-visit session and two months after the end of the treatment period (four months after the start of the treatment). Method of measurement: Patient satisfaction.