NCT03402191Unknown4 期
Comparative Clinical Study Evaluating the Effect of L-arginine Versus Sildenafil in Children With Beta Thalassemia Associated With Pulmonary Hypertension
Sherief Abd-Elsalam1 个研究点 分布在 1 个国家目标入组 60 人开始时间: 2016年7月最近更新:
适应症
干预措施
相关药物
试验速览
- 阶段
- 4 期
- 发起方
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- Number of patients with improvement of pulmonary hypertension
研究概览
简要总结
This study compares L-arginine Versus Sildenafil as treatment for pulmonary hypertension in Children with Beta Thalassemia
详细描述
This study focuses on different lines of treatment for pulmonary hypertension in children with thalassemia as this study discusses the Effect of L-arginine Versus Sildenafil in Children with Beta Thalassemia Associated with Pulmonary Hypertension
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 6 Years 至 18 Years（Child, Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Children with thalassemia and pulmonary hypertension.
排除标准
- •Rheumatic heart diseases.
- •Other comorbid disease
研究组 & 干预措施
L-arginine
Active Comparator
l-arginine for pulmonary hypertension in patients with thalassemia.
干预措施: L-arginine (Drug)
Sildenafil
Active Comparator
Sildenafil for pulmonary hypertension in patients with thalassemia.
干预措施: Sildenafil (Drug)
结局指标
主要结局
Number of patients with improvement of pulmonary hypertension
时间窗: 6 months
patients with improvement of pulmonary hypertension
次要结局
未报告次要终点
研究者
Sherief Abd-Elsalam
PhDTropical Medicine
Tanta University
研究点 (1)
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