Valproic acid for the treatment of Status epilepticus in patients with or without Diabetes Mellitus - a retrospective cohort study

• Conditions: G41; E11; Status epilepticus; Type 2 diabetes mellitus

• Registration Number: DRKS00027836
• Lead Sponsor: niversitätsklinikum Leipzig

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Completion: 2021-12-21
• Study Start: 2022-04-08
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 404

Inclusion Criteria

Patients with the confirmed diagnosis status epilepticus; therapy with valproic acid i.v.; inpatient treatment at the department of neurology of the university hospital Leipzig between 01.01.2008 and 31.12.2020.

Exclusion Criteria

none

Study & Design

• Study Type: observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
rate of stop of the therapy with valproic acid due to safety issues in patients with or without diabetes mellitus

Secondary Outcome Measures

Name	Time	Method
incidence of drug-related side effects; inhospital mortality; functional outcome at discharge from hospital in both subcohorts (patients with or without diabetes mellitus)