Efficacy of oxytocin with placebo and oxytocin with propranol on the labor augmentation.

Not Applicable

• Conditions: Single spontaneous delivery.; Spontaneous vertex delivery

• Registration Number: IRCT138902141096N2
• Lead Sponsor: Vice Chancellor for research-Guilan University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 22 February 2018

Recruitment & Eligibility

• Status: Complete
• Sex: Female
• Target Recruitment: 118

Inclusion Criteria

Inclusion criteria included: Primiparous pregnant women with single fetus and cephalic presentation the top 37 weeks of pregnancy (According to reliable LMP or ultrasound the first trimester) with intact membrance And fetal heart rate between 120 to 160 beats per minute and estimated fetal weight by ultrasound examination or visitors between 2500 and 4000 g and in the active phase of labor had no failure to progress. Exclusion criteria: Multi-parity, History of surgery on the uterus, malpresentation (non-cephalic), Mismatch over maternal fetal pelvis , Fetal distress, including late deceleration (Gradually reducing the minimum and maximum heart rate after completing the contract with the minimum loss rate of 15 and may take over 15 seconds) or prolong deceleration (longs over two minutes and less than 10 minutes) , Suspected macrosomia (Estimated weight over 4000 g) ,polyhydroamnius , IUGR (Estimated fetal weight using ultrasound is lower than the tenth percentile) , Women whit systolic blood pressure 90 mmHg or less And with heart rate <60 beats per minute and Women with a history of these diseases are also excluded: HTN ,Cardiac disease (Cardiac block,CHF , Right ventricular failure secondary to pulmonary hyper tension , Sinus bradycardia, Cardiogenic shock ,Significant aortic or mitral valve disease. And lung disease (Bronchial asthma or bronchospasm, severe chronic obstructive pulmonary disease, allergic rhinitis) Patients with kidney or liver dysfunction, diabetes, patients prone to hypoglycemia, myasthenia Gravis and Wolf - Parkinson – White.

Exclusion Criteria

Not provided

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
The effect of oxytocin with propranolol on augmentation. Timepoint: Every hour. Method of measurement: After entering an active phase of labor the patient is examined vaginally.;The effect of oxytocin without propranolol on augmentation. Timepoint: Every hour. Method of measurement: After entering an active phase of labor the patient is examined vaginally.;The effect of propranolol with and without oxytocin on augmentation. Timepoint: Every hour. Method of measurement: After entering an active phase of labor the patient is examined vaginally.