Clinical study and molecular mechanism of Piwei Peiyuan recipe in the treatment of chronic atrophic gastritis with intestinal metaplasia
- Conditions
- chronic atrophic gastritis with intestinal metaplasia
- Registration Number
- ITMCTR2200005779
- Lead Sponsor
- Second Affiliated Hospital of Anhui University of Traditional Chinese Medicine
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- All
- Target Recruitment
- Not specified
(1) Age: 18-70 years old, no gender limitation; (2) It conforms to the diagnostic criteria of chronic atrophic gastritis with intestinal metaplasia and TCM syndrome of spleen and stomach weakness; (3) Hp negative patients or previous Hp infection, successful eradication treatment for more than six months and no symptomatic infection; (4) Those who voluntarily participate in the clinical trial and give informed consent and sign the informed consent.
(1) complicated with peptic ulcer, pathologically confirmed as high-grade intraepithelial neoplasia or suspected malignant transformation; (2) have a history of severe digestive diseases or abdominal surgery; (3) pregnant and lactating women; (4) serious diseases associated with the study evaluation, such as severe blood diseases, liver disease, heart disease, kidney disease, malignant tumor, etc.; (5) patients with disabilities as prescribed by law; (6) Long-term use of NSAIDS and history of alcoholism; (7) allergic to drugs used in this study; (8) Participants in clinical trials of other drugs in the last 4 weeks; Or have used mofuchun, morodane, folic acid and other preparations in recent 2 weeks; (9) Easy to cause lost visitors.
Study & Design
- Study Type
- Interventional study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method pathological diagnosis;The pathological integral;
- Secondary Outcome Measures
Name Time Method TCM syndrome Integral;Results of gastroscopy;life quality score;serological indicator;Anxiety indicators;