跳至主要内容
临床试验/ISRCTN96755104
ISRCTN96755104已完成4 期

Do xanthine oxidase inhibitors regress left ventricular hypertrophy in diabetes? A double-blind randomised placebo-controlled trial

niversity of Dundee (UK)0 个研究点目标入组 66 人开始时间: 2009年4月20日最近更新:

试验速览

阶段
4 期
状态
已完成
发起方
入组人数
66

研究概览

简要总结

暂无简介。

研究设计

研究类型
Interventional

入排标准

性别
All

入选标准

  • 1. Patients with type 2 diabetes
  • 2. Patients with left ventricular hypertrophy
  • 3. Office target blood pressure less than 150/90 mmHg at recruitment
  • No age or gender restrictions.

排除标准

  • 2. Already on allopurinol
  • 3. Previous adverse reaction to allopurinol
  • 4. Poor kidney function (estimated glomerular filtration rate [eGFR] less than 60 ml/mm)
  • 5. Conditions that exclude magnetic resonance imaging (MRI)
  • 6. Heart failure (left ventricular ejection fraction [LVEF] less than 45%)
  • 7. Cancer or other life threatening illness
  • 8. Pregnancy or breast feeding
  • 9. Unable to provide consent

研究者

发起方
niversity of Dundee (UK)

相似试验

终止
不适用
Impact of icodextrin on the left ventricular hypertrophy in patients with chronic kidney disease on peritoneal dialysisC12.050.351.968.419.780.750.500chronic kidney disease
RBR-2mzhmj2Hospital das Clinicas da Universidade de Sao Paulo
招募中
4 期
Effect of ranolazine on improvement of heart functio
CTRI/2014/01/004332SRM Medical College Hospital50
进行中(未招募)
不适用
The effect of medical treatment (metoprolol) on heart failure caused by aortic regurgitatioThe aim of the present study is therefore to assess the effect of a 6 month treatment with beta-blocker on left ventricular remodeling and function in patients with asymptomatic moderate to severe aortic regurgitation.(ii)Patients in stable clinical situation(iii)Have LVEF >55%, (iv)Have an end diastolic diameter (on echo) of 50-60 mmMedDRA version: 14.1Level: LLTClassification code 10002904Term: Aortic regurgitationSystem Organ Class: 100000004849
EUCTR2007-000518-34-DKRikshospitalet70
招募中
不适用
The Effects of Vasodilators agents on Right Ventricular Energetics in patients with Pulmonary Hypertension: A study using Carbon-11 Acetate PET, oxygen-15 labeled water PET, and biomarkersPulmonary arterial hypertension
JPRN-UMIN000006314Hokkaido University Graduate School of Medicine80
招募中
不适用
The effects of treatment on the right ventricular exertional contractile reserve in chronic tromboembolic pulmonary hypertension patientsChronic tromboembolic pulmonary hypertensionhigh blood pressure in the pulmonary arteries due to chronic pulmonary emboli1001928010037454
NL-OMON45018Vrije Universiteit Medisch Centrum48