Exploring the Relationship Between Serum Vitamin D and Atherosclerosis in Hemodialysis Patients: A Cross-sectional Study
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 90
- 试验地点
- 1
- 主要终点
- Correlation between Serum Vitamin D and Atherosclerosis
研究概览
简要总结
The study aimed to check if there is a link between good vitamin D levels in the blood and subclinical atherosclerosis in people on hemodialysis.
详细描述
Hemodialysis patients with End-Stage Renal Disease (ESRD) face a significantly elevated risk of cardiovascular disease (CVD) due to a complex interplay of factors. A 30-year-old HD patient faces a cardiovascular mortality risk equivalent to that of an 80-year-old in the general population, emphasizing the accelerated aging of the cardiovascular system in ESRD.
Vitamin D may reduce inflammation and modulate immunity, lowering hypertension and dyslipidemia risks and possibly reversing vascular calcification. However, excessive supplementation can cause hypercalcemia.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients with end-stage renal disease (ESRD) who had been on maintenance hemodialysis for at least 6 months.
- •Age of 18 years or older.
- •Patients receiving three weekly dialysis sessions using a bicarbonate-based dialysate with anticoagulants.
排除标准
- •Patients with active infections, malignancies, autoimmune diseases, or pre-existing cardiovascular conditions.
- •Pregnancy.
结局指标
主要结局
Correlation between Serum Vitamin D and Atherosclerosis
时间窗: Immediately post-procedure (Up to 1 hour)
Correlation between Serum Vitamin D and Atherosclerosis was recorded.
次要结局
未报告次要终点
研究者
Ashraf Hassan
Assistant Professor of Internal Medicine and Nephrology, Faculty of Medicine, Ain shams University, Cairo, Egypt.
Ain Shams University