Efficacy and safety of oral methotrexate vs oral tofacitinib in management of oral lichen planus A prospective randomised study - Nil

avneet Singh0 个研究点目标入组 0 人开始时间: 待定最近更新: 2024年7月22日

试验速览

暂无简介。

•1. Patients who are diagnosed case of oral lichen planus with or without skin lesions .
•2. Both sexes - Male and Female.
•3. Age- More than 18 years and less than 60 years

•1. Age less than 18 years or more than 60 years.
•2. Pregnancy, those female patients who are planning for pregnancy in next one month and lactation.
•3. Patients unwilling to give consent to be part of trial.
•4. Patients with active or latent TB.
•5. Patients with anemia, liver disease, kidney disease, GI disease ( diverticulitis, perforation, ulcers ), respiratory disease ( ILD, COPD, pulmonary edema )
•6. Patients with malignancies or lymphoproliferative disorders.
•7. Patients on potent immunosuppressants, biological DMARDS, H/O organ transplant.
•8. Patients with deranged lipid profile.
•9. H/O recent live vaccination.
•10. Family history of melanoma/non melanoma skin disorders.
•11. Alcohol intake, tobacco and smoking.
•12. Obesity.
•13. H/o any thromboembolic event, cardiovascular disease, stroke.

发起方

avneet Singh