JPRN-UMIN000002502已完成1 期
"Add-back" therapy with HSV-TK gene transduced donor lymphocytes after T-cell-depleted haplo-identical hematopoietic stem cell transplantation - Haploidentical transplantation using HSV-TK gene transduced lymphocyte
适应症
试验速览
- 阶段
- 1 期
- 状态
- 已完成
- 入组人数
- 10
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 20years-old 至 60years-old（—）
- 性别
- All
入选标准
- 未提供
排除标准
- •1) Patients unlikely to stop the ongoing ganciclovir administration for the presentation of CMV infection or elevated blood CMV antigen level by the start of conditioning regimen. 2) Patients unlikely to stop the ongoing ACV administration by the start of conditioning regimen. 3) Patients whose ejection franction at rest is less than 50% when measured by echocardiography 4) Patients with diabetes mellitus poorly controlled despite continued insulin therapy 5) Patients with poorly controlled hypertension 6) Patients having treatment-requring allergy or allergy to any drugs used during this study 7) Patients with active infection 8) Patients with uncontrollable evident tumor cell invasion into the central nervous system 9) Patients with active double cancers 10) Patients with previous history of TBI or total lymph node irradiation (TLI) 11) Patienta tested positive for any of HIV antibody, HBs antigen and HCV antibody
研究者
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