Mediastinal Microdialysis in Patients With Oesophageal or Cardia Cancer Treated by Resection
- Conditions
- Anastomotic LeakageEsophageal Cancer
- Registration Number
- NCT00686569
- Lead Sponsor
- Odense University Hospital
- Brief Summary
Postoperative anastomotic leakage is a serious complication in patients with oesophageal or cardia cancer. Early diagnosis and treatment are mandatory. The primary aim of the present study is to investigate the clinical use of mediastinal microdialysis and whether is able to detect anastomotic leakage prior to the development of clinical symptoms.
- Detailed Description
Patients undergoing oesophageal or cardia resection for cancer are monitored by mediastinal microdialysis during the postoperative period. Subcutaneous microdialysis serves as a control. Samples are collected every 4-hour. Samples will be analyzed continuously but the results will not be included in the clinical evaluation of the patient.
A total of 30 patients will be included in this pilot study. The results of the mediastinal microdialyses will be compared with the clinical course in each patient. The results form the uncomplicated courses will be used to define the normal variations in mediastinal microdialysis. This will be compared to results from patients with various complications.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 40
- Histological verified oesophageal or cardia cancer
- Lack of consent, otherwise none
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Early detection of postoperative complications 30 days postoperative
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (2)
Surgical department A, Odense University Hospital
🇩🇰Odense, Denmark
Odense University Hospital, surgical department A
🇩🇰Odense C, Denmark