Comparative Analysis of Aqueous Humor Adipokines in Patients With Glaucoma and Healthy Controls
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 2
- 试验地点
- 1
- 主要终点
- Concentration of adipokines in aqueous humor
研究概览
简要总结
The purpose of this study is to observe whether there are differences in adipokines in the aqueous humor between patients with primary open-angle glaucoma (POAG) and healthy controls
详细描述
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Inclusion criteria: Patients aged 18 years or older, diagnosed with primary open-angle glaucoma (POAG) and healthy controls (who underwent cataract surgery).
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Exclusion criteria:
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Other Ocular Diseases: Patients with concurrent ocular diseases such as macular degeneration, retinal detachment, etc., are excluded.
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Ocular Surgery History: individuals who have undergone intraocular or laser surgery within the past 6 months, except for uncomplicated cataract surgery.
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History of Ocular Trauma or Inflammation
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Systemic Diseases or Mental Disorders: Patients with systemic diseases(e.g., diabetes, rheumatoid arthritis) and those with mental disorders are excluded.
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Pregnancy or Lactation: Females who are pregnant or lactating are excluded.
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Presence of any retinal or optic nerve disease other than glaucoma.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 85 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients aged 18 years or older, diagnosed with primary open-angle glaucoma (POAG) and healthy controls (who underwent cataract surgery).
排除标准
- •Other Ocular Diseases: Patients with concurrent ocular diseases such as macular degeneration, retinal detachment, etc., are excluded.
- •Ocular Surgery History: individuals who have undergone intraocular or laser surgery within the past 6 months, except for uncomplicated cataract surgery.
- •History of Ocular Trauma or Inflammation
- •Systemic Diseases or Mental Disorders: Patients with systemic diseases(e.g., diabetes, rheumatoid arthritis) and those with mental disorders are excluded.
- •Pregnancy or Lactation: Females who are pregnant or lactating are excluded.
- •Presence of any retinal or optic nerve disease other than glaucoma.
结局指标
主要结局
Concentration of adipokines in aqueous humor
时间窗: Cross-sectional baseline
Aqueous humor samples were assessed for adipokines and inflammatory cytokines by Luminex bead-based multiplex array
次要结局
未报告次要终点