Indicated prevention of mental disorders in subjects with initial panic symptomatology: effectiveness and underlying mechanisms of actio

Not Applicable

Recruiting

Lead Sponsor: Technische Universität Dresden, Institut für Klinische Psychologie und Psychotherapie, Professur Behaviorale Epidemiologie

Recruitment & Eligibility

Inclusion Criteria

Healthy adults reporting a fearful spell / panic attack during the past 12 months

Exclusion Criteria

- current treatment (intention) due to psychological problems

- meeting criteria for any 12-month mental disorder, 12-month psychotic or bipolar I disorder, acute suicidality

- severe physical disease (respiratory, cardiac or neurologic disease, epilepsy).

Primary Outcome Measures

Name	Time	Method
Intervention efficacy: Reduction of panic severity from baseline to post-assessment (PD-D, PDSS-SR)<br>Prevention efficacy: Incidence rates for any full-threshold mental disorder from entry exam to 12-month follow-up assessment (DSM-5 CIDI)

Secondary Outcome Measures

Name	Time	Method
Intervention efficacy: Other symptom changes from baseline to post-assessment (BSQ, PAI, ASI, MI, CLQ, DSM-5 CCSM), other clinical changes from baseline to post-assessment (e.g. levels of impairment and disability, DSM-5 CIDI)<br>Prevention efficacy: Incidence and recurrence rates for individual sub-threshold and full-threshold mental disorders from entry exam to follow-up assessment (DSM-5 CIDI), changes in panic severity from post- to follow-up assessment (PD-D, PDSS-SR); other symptom changes from post- to follow-up assessment (BSQ, PAI, ASI, MI, CLQ, DSM-5 CCSM); other clinical changes from post- to follow-up assessment (e.g. levels of impairment and disability, DSM-5 CIDI)<br>Mediator variables: Changes in defensive responsivity to acute threat and potential harm, indicated by different indices of defensive mobilization as derived from experimental paradigms from baseline to post-assessment and post- to follow-up assessment as well as from baseline- to follow-up assessment.<br>