EUCTR2021-002188-23-DK进行中（未招募）1 期
Association between variations in CYP pheno- and genotypes and plasma concentration of chlordiazepoxide in the treatment of alcohol withdrawal symptoms
相关药物
试验速览
- 阶段
- 1 期
- 状态
- 进行中（未招募）
- 入组人数
- 26
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional clinical trial of medicinal product
入排标准
- 性别
- All
入选标准
- •Age =18 years
- •Treatment with minimum 200 mg chlordiazepoxide for alcohol withdrawal symptoms during hospital admission
- •Acute admittance to ICU or ICD due to respiratory insufficiency, impaired consciousness or agitation.
- •Inclusion possible within 6 h of ICU/ICD admission
- •Are the trial subjects under 18? no
- •Number of subjects for this age range:
- •F.1.2 Adults (18-64 years) yes
- •F.1.2.1 Number of subjects for this age range 20
- •F.1.3 Elderly (>=65 years) yes
- •F.1.3.1 Number of subjects for this age range 6
排除标准
- •Allergies to omeprazole and midazolam
- •Treatment with chlordiazepoxide within the first 12 h after inclusion (from blood samples at inclusion until blood samples 12 h after inclusion)
- •Treatment with omeprazole within 1 day prior to ICU/ICD admission
- •Treatment with midazolam within 1 day prior to ICU/ICD admission
- •Cardiac arrest prior to admission
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