Carbon-ion radiotherapy for solitary lymph node recurrence: a retrospective multicenter observational study
Not Applicable
- Conditions
- Solitary lymph node recurrence
- Registration Number
- JPRN-UMIN000027300
- Lead Sponsor
- Hospital of the National Institute of Radiological Sciences, National Institutes for Quantum and Radiological Sciences and Technology
- Brief Summary
A total of 323 patients were enrolled. The 2-year local control (LC) and overall survival (OS) rates after C-ion RT were 85% and 63%, respectively. Only 1 patient developed grade 3 toxicity. Factors such as LN diameter, histology, and history of previous RT did not correlate with LC. Smaller diameters (<30 mm) and numbers of LN metastases as well as longer disease-free intervals post-primary therapy were associated with significantly better OS.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 323
Inclusion Criteria
Not provided
Exclusion Criteria
1)Tumor invasion to GI tract. 2)Severe or active nfections in the irradiated area. 3)Severe concomitant illness.
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 2-year local control, course-specfic survival, and overall survival rates. Incidence of Grade 2 or worse late toxicities
- Secondary Outcome Measures
Name Time Method