Use of Dexmedetomidine in Children Undergoing Oral Maxillofacial Surgery to Decrease Emergence Delirium
试验速览
- 阶段
- 4 期
- 状态
- 撤回
- 发起方
- 试验地点
- 1
- 主要终点
- post anesthesia emergence delirium scale(PAED scale)
研究概览
简要总结
The purpose of this study is to determine whether dexmedetomidine is effective in the treatment of emergence delirium of preschool children undergoing oral maxillofacial surgery.
详细描述
Emergence delirium is a common side effect of sevoflurane anesthesia in children. Dexmedetomidine, because of its sedative and analgesic properties, might be useful for the management of this adverse effect. In the pediatric population, it has been shown to provide sedation for magnetic resonance imaging. Intravenously, it is has been shown to decrease emergence delirium following sevoflurane based anesthesia. The ability to administer a medication intravenously might solve the problem of emergence delirium and emergence agitation posed by the young patients undergoing oral maxillofacial surgery.
研究设计
- 研究类型
- Interventional
- 干预模型
- Sequential
- 主要目的
- Supportive Care
- 盲法
- None
入排标准
- 年龄范围
- 3 Years 至 8 Years（Child）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •preschool children undergoing oral maxillofacial surgery
排除标准
- •mental diseases
- •history of neural system disease
- •sedative medication history
- •anticipated difficult airway
研究组 & 干预措施
dexmedetomidine
intravenously injecting 0.125microgram/kg and 0.25microgram/kg within 10 minutes as soon as the operation begins respectively.
干预措施: dexmedetomidine (Drug)
结局指标
主要结局
post anesthesia emergence delirium scale(PAED scale)
时间窗: 2 hours post-surgery
evaluate children's PAED scale score 2 hours post-surgery
次要结局
- Children's Hospital of Eastern Ontario Pain Scale(CHEOP scale)(2 hours post-surgery)
研究者
Rong Hu
attending in anesthesiology department
Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University