Effects of Oral Tranexamic Acid on Short Term Postoperative Outcomes Following Total Shoulder Arthroplasty

Phase 3

Not yet recruiting

• Conditions: Shoulder Arthroplasty
• Interventions: Drug: oral tranexamic acid; Drug: Placebo

• Registration Number: NCT06902714
• Lead Sponsor: University of Alabama at Birmingham

Brief Summary

The purpose of this clinical trial is to evaluate the short-term clinical outcomes of patients undergoing total shoulder arthroplasty who receive an extended postoperative course of oral tranexamic acid

Detailed Description

Not available

Study Timeline

• Status Verified: 2025-03
• Study First Submitted: 2025-03-18
• Study First Submitted QC: 2025-03-27
• Last Update Submitted: 2025-03-27
• Study First Posted: 2025-03-30
• Last Update Posted: 2025-03-30
• Study Start: 2025-07
• Primary Completion: 2026-07
• Study Completion: 2026-12

Recruitment & Eligibility

• Status: NOT_YET_RECRUITING
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

• Skeletally mature patients (ages 18-79) undergoing primary total shoulder arthroplasty

Exclusion Criteria

• Patients with Cancer, venous thromboembolism, stroke, heart disease, pregnant or nursing, allergic to TXA, current tobacco use, anticoagulants other than aspirin.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
oral tranexamic acid	oral tranexamic acid	-
Oral Placebo	Placebo	-

Primary Outcome Measures

Name	Time	Method
VAS	2 weeks	visual analog scale

Trial Locations

Locations (1)

University of Alabama at Birmingham; 🇺🇸 Birmingham, Alabama, United States