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临床试验/NCT04370080
NCT04370080已完成不适用

Silver Diamine Fluoride Treatment of Active Root Caries Lesions in Older Adults: A Case Series

Roseman University of Health Sciences0 个研究点目标入组 63 人开始时间: 2017年1月3日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
63
主要终点
Dental caries lesion activity 1

研究概览

简要总结

The authors conducted a case series to determine the outcomes of treatment of root surface caries lesions when the teeth were treated topically with 38% silver diamine fluoride.

详细描述

The study is a prospective, single center case series. The cases were consecutive. Participation was offered to every patient who qualified based on age and the presence of an active lesion in a root surfaces, in a furcation, or under an individual crown or crown abutment for a fixed prosthesis. The study was conducted at the dental clinic of the Roseman College of Dental Medicine in South Jordan, Utah. The University of California, San Francisco protocol for applying topical silver diamine fluoride was adapted for use with these patients. Lesions were flushed with water and then dried with compressed air, isolated with cotton rolls, and then 38% silver diamine fluoride (Advantage Arrest, Elevate Oral Care, West Palm Beach, FL) was applied repeatedly for two minutes with the manufacturer supplied dental applicator. The silver diamine fluoride was stored under the manufacturer's recommended conditions. If the patient complained about the taste, the lesion was coated with sodium fluoride varnish. All of the lesions were reevaluated for dental caries lesion activity about every six months and retreated regardless of their arrest status. Follow-up was for 30 months or until loss to follow-up.

研究设计

研究类型
Interventional
分配方式
Na
干预模型
Single Group
主要目的
Treatment
盲法
None

入排标准

年龄范围
55 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • At least 1 active root surface caries lesion by Nyvad criteria

排除标准

  • 未提供

结局指标

主要结局

Dental caries lesion activity 1

时间窗: 6-12 months

Nyvad score based on visual/tactile examination

Dental caries lesion activity 2

时间窗: <6 months

Nyvad score based on visual/tactile examination

Dental caries lesion activity 3

时间窗: 12-18 months

Nyvad score based on visual/tactile examination

Dental caries lesion activity 4

时间窗: 18-24 months

Nyvad score based on visual/tactile examination

Dental caries lesion activity 5

时间窗: 24-30 months

Nyvad score based on visual/tactile examination

次要结局

  • Caries lesion fluorescence 4(18-24 months)
  • Caries lesion fluorescence 5(24-30 months)
  • Caries lesion fluorescence 1(<6 months)
  • Caries lesion fluorescence 3(12-18 months)
  • Caries lesion fluorescence 2(6-12 months)

研究者

发起方
Roseman University of Health Sciences
申办方类型
Other
责任方
Principal Investigator
主要研究者

David Prince

Associate Professor

Roseman University of Health Sciences

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