Opportunistic Salpingectomy at the Time of Benign Laparoscopic Hysterectomy

Completed

• Conditions: Benign Laparoscopic Hysterectomy; Systematic Salpingectomy
• Interventions: Other: Histopathologic tube anomalies

• Registration Number: NCT03921138
• Lead Sponsor: Hospices Civils de Lyon

Brief Summary

In this prospective study, patients who underwent benign laparoscopic hysterectomy with systematic salpingectomy were included. The aim of this study is to assess the prevalence of tubal histopathological abnormalities such as Serous Tubal Intraepithelial Carcinoma (STIC) and tumor protein 53 (p53) signatures) as well as the prevalence of perioperative and postoperative complications related to opportunistic laparoscopic salpingectomy in a low risk population. The hypothesis is that prophylactic salpingectomy during benign laparoscopic hysterectomy is both feasible and innocuous. Peri- and postoperative complications, duration of salpingectomy and post-salpingectomy blood loss, histopathological and immunohistochemical analysis with anti-p53 antibody were evaluated.

Detailed Description

Not available

Study Timeline

• Study Start: 2014-01-31
• Primary Completion: 2016-01-31
• Study Completion: 2016-01-31
• Status Verified: 2019-04
• Study First Submitted: 2019-04-16
• Study First Submitted QC: 2019-04-16
• Last Update Submitted: 2019-04-16
• Study First Posted: 2019-04-19
• Last Update Posted: 2019-04-19

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Female
• Target Recruitment: 100

Inclusion Criteria

• patients who underwent benign laparoscopic hysterectomy with systematic salpingectomy

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Exclusion Criteria

• Hysterectomy in a context of gynecologic cancer
• Hysterectomy not carried out using laparoscopy
• Fimbriated end missing or damaged or impossible for pathologist to analyze

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Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Benign laparoscopic hysterectomy	Histopathologic tube anomalies	Patients who underwent benign laparoscopic hysterectomy with systematic salpingectomy

Primary Outcome Measures

Name	Time	Method
Histopathologic tube anomalies	day 1 of surgery	Prevalence of histopathologic tube anomalies (Serous Tubal Intraepithelial Carcinoma STIC or tumor protein 53 (p53) lesion)