The effectiveness of vitamin C and thiamine administration method in the improvement and prognosis of shock patients 1 month to 15 years

Phase 3

Recruiting

• Conditions: Shock.; Shock, unspecified; R57.9

• Registration Number: IRCT20200825048515N61
• Lead Sponsor: Esfahan University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 21 November 2022

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 270

Inclusion Criteria

Children from 1 month to 15 years
Suffering from shock (other than obstructive shock)
Need vasopressors to maintain at least 5% of blood pressure percentile for age
Parents' consent to participate in the study

Exclusion Criteria

Having active gastrointestinal bleeding

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
The amount of Vasopressor requirement. Timepoint: During the intervention. Method of measurement: Number of vasopressor injections.;Ventilator requirement. Timepoint: During the intervention. Method of measurement: PaCo2<50% and pH<7.3.

Secondary Outcome Measures

Name	Time	Method
Blood Creatinine. Timepoint: In the first four days of hospitalization. Method of measurement: Blood test.;C-reactive protein (CRP). Timepoint: In the first four days of hospitalization. Method of measurement: Blood test.;White blood cell. Timepoint: In the first four days of hospitalization. Method of measurement: Blood test.;Lactate. Timepoint: In the first four days of hospitalization. Method of measurement: Blood test.