Improving Weight Loss Outcomes for Binge Eating Disorder.
- Conditions
- Weight LossBinge EatingEating DisorderBinge-Eating Disorder
- Interventions
- Behavioral: Acceptance-Based Behavioral Weight Loss Therapy for BEDBehavioral: Standard Behavior Therapy
- Registration Number
- NCT03712462
- Lead Sponsor
- Drexel University
- Brief Summary
This study aims to develop and evaluate the efficacy of a behavioral weight loss treatment approach for individuals with binge eating disorder to both reduce their binge eating behaviors and lose weight.
- Detailed Description
In the current study, we propose to (a) compare the efficacy of an acceptance-based behavioral treatment (ABBT) that targets both binge eating and weight loss in patients with binge eating disorder (BED) to a Standard Behavioral Weight Loss Treatment (SBT), (b) evaluate the extent to which ABBT and SBT target shared maintenance factors for binge eating and overeating episodes, and (c) assess whether treatment efficacy is moderated by baseline values of constructs targeted in ABBT. Our study will be the first to evaluate an ABBT for BED designed to 1) address maintenance factors that give rise to both binge eating episodes and overeating episodes without loss of control and 2) increase adherence to BWL prescriptions.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 126
- Meet the DSM-5 criteria for Binge Eating Disorder
- Have a BMI range of 27-50kg/m2
- are unable to fluently speak, write, and read English
- are currently experiencing severe psychopathology that would limit their ability to engage in study (e.g., suicidality, substance use disorder, psychotic disorder)
- are unable to engage in moderate physical activity (i.e., walk 2 blocks without rest)
- have a medical condition (e.g., acute coronary syndrome, type I diabetes) that would pose a risk to the participant during intervention, cause a change in weight, or limit ability to comply with the recommendations of the program
- Pregnant or planning to become pregnant in the next 2 years
- Recently began a course of or changed the dosage of medication that can cause significant change in weight
- Have a history of bariatric surgery
- Have had weight loss of > 5% in the past 6 months
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description ABBT Weight Loss Therapy for BED Acceptance-Based Behavioral Weight Loss Therapy for BED Acceptance-Based Behavioral Weight Loss Therapy for BED Standard Behavior Therapy Standard Behavior Therapy Standard Behavioral Weight Loss Therapy
- Primary Outcome Measures
Name Time Method Weight Loss Changes from baseline assessment (before beginning treatment), to post-treatment assessment (1 year after baseline assessment), to follow-up assessment (2 years after baseline assessment) Between-group changes in percent weight loss from baseline 1 month, 3 months, and 6 months into the study, at post-treatment (1 year after baseline) and at the one year follow-up assessment (2 years after the baseline).
- Secondary Outcome Measures
Name Time Method Eating Disorder Examination Questionnaire Baseline, Post-Treatment (1 year after baseline), and 1 Year Follow-Up (2 years after baseline) The Eating Disorder Examination Questionnaire measures eating pathology. The EDE-Q yields four subscale scores: Restraint, Eating Concern, Shape Concern, and Weight Concern. The possible score range for each subscale is 0 to 6. The total score may also be reported (determined by averaging the subscale scores); the score range for the total score is also 0 to 6. For subscale scores and total score, higher scores indicate more severe pathology. The restraint sub-scale of the EDE-Q will be used to assess utilization of skills related to reducing dietary restraint.
Assessing changes in EDE Global score.
Trial Locations
- Locations (1)
Drexel University, Stratton Hall
🇺🇸Philadelphia, Pennsylvania, United States