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Improving Weight Loss Outcomes for Binge Eating Disorder.

Not Applicable
Completed
Conditions
Weight Loss
Binge Eating
Eating Disorder
Binge-Eating Disorder
Interventions
Behavioral: Acceptance-Based Behavioral Weight Loss Therapy for BED
Behavioral: Standard Behavior Therapy
Registration Number
NCT03712462
Lead Sponsor
Drexel University
Brief Summary

This study aims to develop and evaluate the efficacy of a behavioral weight loss treatment approach for individuals with binge eating disorder to both reduce their binge eating behaviors and lose weight.

Detailed Description

In the current study, we propose to (a) compare the efficacy of an acceptance-based behavioral treatment (ABBT) that targets both binge eating and weight loss in patients with binge eating disorder (BED) to a Standard Behavioral Weight Loss Treatment (SBT), (b) evaluate the extent to which ABBT and SBT target shared maintenance factors for binge eating and overeating episodes, and (c) assess whether treatment efficacy is moderated by baseline values of constructs targeted in ABBT. Our study will be the first to evaluate an ABBT for BED designed to 1) address maintenance factors that give rise to both binge eating episodes and overeating episodes without loss of control and 2) increase adherence to BWL prescriptions.

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
126
Inclusion Criteria
  • Meet the DSM-5 criteria for Binge Eating Disorder
  • Have a BMI range of 27-50kg/m2
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Exclusion Criteria
  • are unable to fluently speak, write, and read English
  • are currently experiencing severe psychopathology that would limit their ability to engage in study (e.g., suicidality, substance use disorder, psychotic disorder)
  • are unable to engage in moderate physical activity (i.e., walk 2 blocks without rest)
  • have a medical condition (e.g., acute coronary syndrome, type I diabetes) that would pose a risk to the participant during intervention, cause a change in weight, or limit ability to comply with the recommendations of the program
  • Pregnant or planning to become pregnant in the next 2 years
  • Recently began a course of or changed the dosage of medication that can cause significant change in weight
  • Have a history of bariatric surgery
  • Have had weight loss of > 5% in the past 6 months
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Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
ABBT Weight Loss Therapy for BEDAcceptance-Based Behavioral Weight Loss Therapy for BEDAcceptance-Based Behavioral Weight Loss Therapy for BED
Standard Behavior TherapyStandard Behavior TherapyStandard Behavioral Weight Loss Therapy
Primary Outcome Measures
NameTimeMethod
Weight LossChanges from baseline assessment (before beginning treatment), to post-treatment assessment (1 year after baseline assessment), to follow-up assessment (2 years after baseline assessment)

Between-group changes in percent weight loss from baseline 1 month, 3 months, and 6 months into the study, at post-treatment (1 year after baseline) and at the one year follow-up assessment (2 years after the baseline).

Secondary Outcome Measures
NameTimeMethod
Eating Disorder Examination QuestionnaireBaseline, Post-Treatment (1 year after baseline), and 1 Year Follow-Up (2 years after baseline)

The Eating Disorder Examination Questionnaire measures eating pathology. The EDE-Q yields four subscale scores: Restraint, Eating Concern, Shape Concern, and Weight Concern. The possible score range for each subscale is 0 to 6. The total score may also be reported (determined by averaging the subscale scores); the score range for the total score is also 0 to 6. For subscale scores and total score, higher scores indicate more severe pathology. The restraint sub-scale of the EDE-Q will be used to assess utilization of skills related to reducing dietary restraint.

Assessing changes in EDE Global score.

Trial Locations

Locations (1)

Drexel University, Stratton Hall

🇺🇸

Philadelphia, Pennsylvania, United States

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