Phase II Study of Pemetrexed in Combination with Carboplatin Followed by Pemetrexed Maintenance Therapy for Elderly Advanced Non-squamous and Non-small Cell Lung Cancer.
Phase 2
Recruiting
- Conditions
- on-squamous non-small-cell lung cancer
- Registration Number
- JPRN-UMIN000006139
- Lead Sponsor
- Tochigi Thoracic Oncology Research Organization
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 50
Inclusion Criteria
Not provided
Exclusion Criteria
(1)Patients with other clinically significant complications; for example, uncontrollable diabetes and hypertension. (2)Active severe infections. (3)Patients with symptomatic brain metastasis . (4)Patients with massive pleural or pericardial effusion. (5)With prior unapproved drugs or investigational new drugs. (6)Not appropriate to receive the folic acid and vitamin B12 formulation. (7)With peripheral nerves >= grade 2 at enrollment. (8)Continues to NSAIDs during this study. (9)Inappropriate patients for this study judged by the physicians.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method progression free survival
- Secondary Outcome Measures
Name Time Method response rate, safety, overall survival, 1 year survival