Determining factors of prognosis and morbidity in Chronic Chagas Heart Disease - phase III
- Conditions
- Cardiovascular diseasesHeart DiseasesVentricular DysfunctionC14.280C14.280.945
- Registration Number
- RBR-9gm9bz
- Lead Sponsor
- niversidade Federal de Minas Gerais
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Not specified
- Target Recruitment
- Not specified
Diagnosis of Chagas disease by at least two of the three positive serological tests for Trypanosoma cruzi (indirect immunofluorescence, indirect hemoglutination and ELISA). Present a stable clinical condition, defined as no acute exacerbation of heart disease in the last three months. Presence of cardiac involvement defined, on echocardiogram, by the presence of left ventricular dysfunction (ejection fraction lower 52% for males and 54% for females). Presence of clinical signs and symptoms of heart failure (NYHA II and III). Not being a smoker and denying routine exposure to smoking
Presence of inspiratory muscle weakness defined with maximum inspiratory pressure values lower 70% of predicted. Be aged between 30 and 60 years. Be sedentary according to the International Physical Activity Questionnaire (IPAQ). Not having previous episodes of stroke and not having pulmonary, renal pathologies, musculoskeletal limitations and diabetes mellitus, conditions that alter the ability to perform functional tests.
Warm-up activities before carrying out stress tests as well as any other contraindications to the maximum and submaximal tests.
Failure to perform the study's evaluation procedures. Only for the experimental group: do not perform inspiratory muscle training for two days in the same week (at home) or are absent from two supervised sessions during training.
Study & Design
- Study Type
- Intervention
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method