Determining factors of prognosis and morbidity in Chronic Chagas Heart Disease - phase III - DCHD: Dilated Chagasic Heart Disease

niversidade Federal de Minas Gerais0 个研究点开始时间: 2020年6月12日最近更新: 2023年5月29日

试验速览

暂无简介。

•Diagnosis of Chagas disease by at least two of the three positive serological tests for Trypanosoma cruzi (indirect immunofluorescence, indirect hemoglutination and ELISA). Present a stable clinical condition, defined as no acute exacerbation of heart disease in the last three months. Presence of cardiac involvement defined, on echocardiogram, by the presence of left ventricular dysfunction (ejection fraction lower 52% for males and 54% for females). Presence of clinical signs and symptoms of heart failure (NYHA II and III). Not being a smoker and denying routine exposure to smoking
•Presence of inspiratory muscle weakness defined with maximum inspiratory pressure values lower 70% of predicted. Be aged between 30 and 60 years. Be sedentary according to the International Physical Activity Questionnaire (IPAQ). Not having previous episodes of stroke and not having pulmonary, renal pathologies, musculoskeletal limitations and diabetes mellitus, conditions that alter the ability to perform functional tests.

•Warm-up activities before carrying out stress tests as well as any other contraindications to the maximum and submaximal tests.
•Failure to perform the study's evaluation procedures. Only for the experimental group: do not perform inspiratory muscle training for two days in the same week (at home) or are absent from two supervised sessions during training.

发起方

niversidade Federal de Minas Gerais