RBR-9gm9bz
Recruiting
Phase 3
Determining factors of prognosis and morbidity in Chronic Chagas Heart Disease - phase III - DCHD: Dilated Chagasic Heart Disease
niversidade Federal de Minas Gerais0 sitesJune 12, 2020
Overview
- Phase
- Phase 3
- Intervention
- Not specified
- Conditions
- Not specified
- Sponsor
- niversidade Federal de Minas Gerais
- Status
- Recruiting
- Last Updated
- 2 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Diagnosis of Chagas disease by at least two of the three positive serological tests for Trypanosoma cruzi (indirect immunofluorescence, indirect hemoglutination and ELISA). Present a stable clinical condition, defined as no acute exacerbation of heart disease in the last three months. Presence of cardiac involvement defined, on echocardiogram, by the presence of left ventricular dysfunction (ejection fraction lower 52% for males and 54% for females). Presence of clinical signs and symptoms of heart failure (NYHA II and III). Not being a smoker and denying routine exposure to smoking
- •Presence of inspiratory muscle weakness defined with maximum inspiratory pressure values lower 70% of predicted. Be aged between 30 and 60 years. Be sedentary according to the International Physical Activity Questionnaire (IPAQ). Not having previous episodes of stroke and not having pulmonary, renal pathologies, musculoskeletal limitations and diabetes mellitus, conditions that alter the ability to perform functional tests.
Exclusion Criteria
- •Warm\-up activities before carrying out stress tests as well as any other contraindications to the maximum and submaximal tests.
- •Failure to perform the study's evaluation procedures. Only for the experimental group: do not perform inspiratory muscle training for two days in the same week (at home) or are absent from two supervised sessions during training.
Outcomes
Primary Outcomes
Not specified
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