NCT01796145进行中（未招募）不适用
A Study to Evaluate the Impact of Liver Stiffness on Treatment Outcome of Hepatocellular Carcinoma
适应症
试验速览
- 阶段
- 不适用
- 状态
- 进行中（未招募）
- 入组人数
- 207
- 试验地点
- 1
- 主要终点
- Overall survival
研究概览
简要总结
In patients with HCC undergoing therapy 1. We aim to determine the prognostic significance of liver stiffness in patients with HCC 2. We aim to determine the rate and severity of complications of treatment and its association with liver stiffness in patients with HCC
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Parallel
- 主要目的
- Other
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Clinical diagnosis of HCC
- •Patients who are scheduled to undergo therapy, either TACE systemic therapy or surgery
- •For TACE cohort, patients undergoing first cycle TACE are eligible.
- •For systemic therapy cohort, patients undergoing first-line systemic therapy are eligible.
- •For surgery cohort, patient undergoing surgery are eligible.
- •Prior surgery or loco-ablative therapy (e.g. Radiofrequency ablation, microwave, percutaneous ethanol injection) is allowed
- •Child's A to Child's C liver function
排除标准
- •ECOG performance status > 2
- •Poorly controlled ascites
结局指标
主要结局
Overall survival
时间窗: 3 years
次要结局
- Liver stiffness (kPa)(2 years)
- Rate and grade of treatment complications(2 years)
研究者
CCTU
Comprehensive Cancer Trials Unit
Chinese University of Hong Kong
研究点 (1)
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