The efficacy of combination of Olanzapine, Aprepitant, Palonosetron and dexamethasone for the prevention of nausea and vomiting in patients receiving autologous peripheral blood stem cell transplantation for multiple myeloma
Phase 2
- Conditions
- multiple myeloma
- Registration Number
- JPRN-UMIN000035970
- Lead Sponsor
- Hitachi general hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 52
Inclusion Criteria
Not provided
Exclusion Criteria
1)Uncontrolled active infection. 2)Active gastrointestinal ulcer. 3)Serious psychiatric illness. 4)Patient who is judged to be medically unfit by physician.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Complete response rate for the delayed phase (24-120 hours), defined as no emetic episodes and no use of rescue medication
- Secondary Outcome Measures
Name Time Method Complete response rate for the acute phase (0-24 hours) and the overall phase (0-120 hours). Complete control rate for the acute, delayed and overall phase.