A Comparative Clinical Study Of Eranda Beeja Payasa And Rasanadi Guggul In The Management Of Gridhrasi With Special Reference To Sciatica

This randomized, open-label, comparative clinical study evaluates the efficacy of Eranda Beeja Payas in the management of Gridhrasi (sciatica) in comparison with Rasanadi Guggul, based on Ayurvedic principles. Gridhrasi, described in classical texts as a Vata Vyadhi presenting with Stambha, Ruk, Toda, and Spandana, closely parallels modern sciatica caused by compression or irritation of the sciatic nerve. Considering the limitations of contemporary treatments and the high prevalence of low back pain and sciatica, this study aims to explore an effective, non-invasive Ayurvedic intervention.

A total of 30 patients (aged 25–60 years) meeting diagnostic criteria of Gridhrasi will be randomly allocated into two groups of 15 each. Group A will receive Eranda Beeja Payas prepared as per classical guidelines, with dosage tailored to the patient’s Agni for 30 days. Group B will receive Rasanadi Guggul (500 mg BD). Follow-ups will occur on Day 15, 30, and 45, including drug-free follow-up on Day 45. Assessment will be based on both subjective parameters (Toda, Ruk, Stambha, Spandana, Gaurava, Aruchi, Tandra) and objective parameters (VAS score, SLR test, Bragard’s test). Data will be statistically analyzed to determine comparative therapeutic efficacy.

The primary objective is to assess whether Eranda Beeja Payas offers significant improvement in symptoms of Gridhrasi relative to Rasanadi Guggul. Results will contribute to evidence-based validation of classical Ayurvedic formulations used in Vata-Vyadhi management.