A Comparative Clinical Study Of Eranda Beeja Payasa And Rasanadi Guggul In The Management Of Gridhrasi With Special Reference To Sciatica

Jammu Institute Of Ayurveda And Research1 个研究点分布在 1 个国家目标入组 30 人开始时间: 2026年5月1日最近更新: 2025年12月22日

试验速览

阶段: 2 期
状态: 尚未招募
发起方
入组人数: 30
试验地点: 1
主要终点: TODA,RUK, STAMBHA, SPANDANA, GAURAVA, ARUCHI, TANDRA

研究概览研究设计入排标准结局指标研究者研究点记录与标识符相似试验

研究概览

简要总结

This randomized, open-label, comparative clinical study evaluates the efficacy of Eranda Beeja Payas in the management of Gridhrasi (sciatica) in comparison with Rasanadi Guggul, based on Ayurvedic principles. Gridhrasi, described in classical texts as a Vata Vyadhi presenting with Stambha, Ruk, Toda, and Spandana, closely parallels modern sciatica caused by compression or irritation of the sciatic nerve. Considering the limitations of contemporary treatments and the high prevalence of low back pain and sciatica, this study aims to explore an effective, non-invasive Ayurvedic intervention.

A total of 30 patients (aged 25–60 years) meeting diagnostic criteria of Gridhrasi will be randomly allocated into two groups of 15 each. Group A will receive Eranda Beeja Payas prepared as per classical guidelines, with dosage tailored to the patient’s Agni for 30 days. Group B will receive Rasanadi Guggul (500 mg BD). Follow-ups will occur on Day 15, 30, and 45, including drug-free follow-up on Day 45. Assessment will be based on both subjective parameters (Toda, Ruk, Stambha, Spandana, Gaurava, Aruchi, Tandra) and objective parameters (VAS score, SLR test, Bragard’s test). Data will be statistically analyzed to determine comparative therapeutic efficacy.

The primary objective is to assess whether Eranda Beeja Payas offers significant improvement in symptoms of Gridhrasi relative to Rasanadi Guggul. Results will contribute to evidence-based validation of classical Ayurvedic formulations used in Vata-Vyadhi management.

研究设计

研究类型: Interventional
分配方式: Randomized
盲法: None

入排标准

年龄范围: 25.00 Year(s) 至 60.00 Year(s)（—）
性别: All

入选标准

•1.Patients between the age group of 25 – 60 years.
•2.Patient representing signs and symptoms of Gridhrasi who are willing to participate in study.
•3.Subjects willing to participate with written informed consent, which is conveyed in the language which the subject can understand.
•4.Both males and female will be selected.

排除标准

•1.Age below 25 years and above 60 years.
•2.Patients suffering from Cardiac Diseases.
•3.Uncontrolled Diabetes Mellitus, Hypertension.
•4.Cancer of Lumbo-Sacral spine.
•5.Tuberculosis of vertebral column.
•6.Pregnant and lactating women.
•Patient suffering from Ankylosing spondylitis, sacroiliac arthritis, herpes simplex infection causing radiating pain, disc prolapse, degenerative changes, bony osteophytic growth.
•8.Any trauma related to Lumbo-sacral spine.