JPRN-UMIN000027523已完成未知
oncontrolled open-label exploratory clinical trial of additional infliximab therapy for patients with refractory Kawasaki disease who are refractory to intravenous immunoglobulin therapy, additional intravenous immunoglobulin therapy and first infliximab therapy. - Noncontrolled open-label exploratory clinical trial of additional infliximab therapy for patients with refractory Kawasaki disease who are refractory to intravenous immunoglobulin therapy, additional intravenous immunoglobulin therapy and first infliximab therapy.
适应症
试验速览
- 阶段
- 未知
- 状态
- 已完成
- 入组人数
- 5
研究概览
简要总结
Additional infliximab was administered to 5 patients with refractory Kawasaki disease. Fever was resolved in 2 cases and it was judged that there was an effect. The other 3 cases were judged to be refractory due to fever persistence and additional treatment was performed.
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 1years-old 至 ot applicable（—）
- 性别
- All
入选标准
- 未提供
排除标准
- •1. Example which was ineligible for the first infliximab administration 2. Patients with severe infectious complications or sepsis 3. Patients with a history of demyelinating disease 4. Patients with a history of malignant tumors 5. Patients with a history of tuberculosis infection or tuberculosis 6. Patients with less than 6 months after BCG vaccination 7. Patients with less than 1 month after live vaccination 8. Patients who showed allergy symptoms in the first infliximab administration 9. Patients with congestive heart failure 10. Patients who are receiving steroids or other immunosuppressants 11. In addition, patients whose research managers judged inappropriate as subjects
研究者
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