DNA Analysis of Discarded Media Drops From the Clinical IVF Cycles

Recruiting

• Conditions: Infertility

• Registration Number: NCT03717441
• Lead Sponsor: Colorado Center for Reproductive Medicine

Brief Summary

Performing DNA analysis of discarded media drops from the clinical IVF cycles completed in our Center

Detailed Description

The purpose of this research study is to investigate for the presence of DNA in the surrounding media that is remaining after human clinical IVF cycles, to have a non-invasive way of obtaining markers of embryo chromosome numeration. Media recovered from the clinical IVF laboratory is typically discarded during an IVF cycle. Genomic technologies will be used to analyze the otherwise discarded media drop for chromosome counting.

Study Timeline

• Study Start: 2018-10-22
• Study First Submitted: 2018-10-22
• Study First Submitted QC: 2018-10-22
• Study First Posted: 2018-10-24
• Status Verified: 2024-02
• Last Update Submitted: 2024-02-28
• Last Update Posted: 2024-02-29
• Primary Completion: 2025-12-15
• Study Completion: 2026-06-15

Recruitment & Eligibility

• Status: RECRUITING
• Sex: Female
• Target Recruitment: 250

Inclusion Criteria

• Any women undergoing an In Vitro Fertilization cycle (IVF) at the Colorado Center for Reproductive Medicine that is also having Comprehensive Chromosomal Screening (CCS) of embryos

Exclusion Criteria

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
DNA Analysis of discarded media drops form the clinical IVF Cycles	1 day	Analyze media drop for presence of DNA to obtain embryo chromosome numeration

Trial Locations

Locations (1)

Colorado Center for Reproductive Medicine; 🇺🇸 Lone Tree, Colorado, United States