Brain Activity During Sexual Behavior in Patients With Primary Premature Ejaculation a Clinical Trial
- Conditions
- Premature Ejaculation
- Registration Number
- NCT06570135
- Lead Sponsor
- Xijing Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Not yet recruiting
- Sex
- Male
- Target Recruitment
- 20
Inclusion Criteria (primary premature ejaculation subjects):<br><br> - patients' age varied from 18 to 45 years;<br><br> - patients met the 2014 International Society for Sexual Medicine (ISSM) definition<br> criteria for PPE;<br><br> - patients had a stable, heterosexual relationship with a single sexually active<br> female partner for at least 6 months and with at least two sexual intercourses a<br> week and kept stable during the study period;<br><br> - Patients with premature ejaculation lasting longer than 6 months;<br><br> - patients were identified if their scores were higher than 9 on the Chinese version<br> of Premature Ejaculation Diagnostic Tool (PEDT);<br><br> - patients had no history of any previous therapies for PE or had recently stopped the<br> therapies for at least 3 months<br><br> - patients had fully informed consent, signed informed consent form<br><br>Inclusion Criteria (Non-premature ejaculation subjects):<br><br> - Men between the ages of 18-45 years were included according to an age difference of<br> <3 years between each patient and the primary premature ejaculation group, and if<br> more than one volunteer was eligible at the same time, the one with the closest age<br> was selected;<br><br> - Patient does not meet the 2014 International Society for Sexual Medicine (ISSM)<br> criteria for defining premature ejaculation;<br><br> - patients had a stable, heterosexual relationship with a single sexually active<br> female partner for at least 6 months and with at least two sexual intercourses a<br> week and kept stable during the study period;<br><br> - patients had fully informed consent, signed informed consent form;<br><br>Exclusion Criteria:<br><br> - patients were diagnosed with secondary PE, variable PE, and subjective PE;<br><br> - patients were using medications for endocrinological, metabolic, chronic systemic,<br> or psychiatric diseases;<br><br> - patients were abusing alcohol or illegal drugs;<br><br> - patients were diagnosed with erectile dysfunction (ED) if their scores were <21 on<br> the abridged five-item International Index of Erectile Function (IIEF-5)<br><br> - patients were diagnosed with sexual hormone abnormalities, hyperthyroidism,<br> hypothyroidism, Peyronie's disease, prostatitis, urethritis, or urinary tract<br> infection;<br><br> - patients with head injuries that prevent them from completing near-infrared light<br> brain function imaging<br><br> - Patients with severe schizophrenia, anxiety, depression or other neurological<br> symptoms or poor compliance
Not provided
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Results of near-infrared brain functional imaging
- Secondary Outcome Measures
Name Time Method