NCT05491824Unknown不适用
Bio-Repository of DNA in Stroke: an Epidemiological and Genetic Study
Royal Holloway University1 个研究点 分布在 1 个国家目标入组 7,500 人开始时间: 2005年6月11日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 7,500
- 试验地点
- 1
- 主要终点
- Identify novel gene loci associated with different types of stroke
研究概览
简要总结
The Bio-Repository of DNA in Stroke (BRAINS) recruits all subtypes of stroke as well as controls from two different continents, Europe and Asia. Subjects recruited from the United Kingdom (UK) will include stroke patients of European ancestry as well as British South Asians. Stroke subjects from South Asia will be recruited from India and Sri Lanka. Subjects are also recruited in Qatar. South Asian cases will also have control subjects recruited.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients should be aged > 18 years at the time of enrolment.
- •Diagnosis of haemorrhagic or ischemic stroke using World Health Organization guidelines confirmed by clinical examination and imaging (CT or MRI).
- •All patients with cerebral arteriovascular malformations and aneurysms.
- •South Asian or Caucasian ethnic backgrounds.
- •Patient or relative written informed consent.
排除标准
- •Unable to provide consent themselves or through surrogate.
- •Stroke not defined on CT or MRI.
- •Inclusion Criteria:
- •Patients should be aged > 18 years at the time of enrolment.
- •No previous history of stroke.
- •able to provide written consent.
结局指标
主要结局
Identify novel gene loci associated with different types of stroke
时间窗: 5 years
DNA repository of highly phenotyped stroke patients
时间窗: 5 years
次要结局
未报告次要终点
研究者
Pankaj Sharma, MD PhD
Professor
Royal Holloway University
研究点 (1)
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