Massage With Senna-based Laxatives Versus Senna-based Laxatives in Managing Overflow Retentive Stool Incontinence in Pediatrics
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 50
- 试验地点
- 2
- 主要终点
- starting dose
研究概览
简要总结
This study aimed to evaluate the effect of abdominal massage with senna-based laxative in managing overflow retentive stool incontinence in pediatrics.
详细描述
Much attention has been devoted to children with overflow retentive stool incontinence (ORSI) by the pediatric surgeons, as the referral of such cases from pediatric facilities is constantly increasing. An important initial step in managing these children is the exclusion of Hirschsprung's disease starting by water-soluble contrast enema.
Conservative management of ORIS is generally successful. The aim of the treatment is to achieve and maintain regular bowel movements free of symptoms Laxatives remain the mainstay of maintenance therapy of ORSI; yet, there is no standard laxative therapy despite the varieties of medication currently available. New information to these queries can be beneficial to medical staff involved in managing overflow retentive stool incontinence in pediatrics, Possibly it may add new guideline of treatment with more good result , short time and decrease the laxative dose.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Outcomes Assessor)
盲法说明
Blinding process to participants and care providers was impossible due to the nature of intervention therapy. Data were analyzed by an impartial statistician (outcomes assessor), referring to each arm with an encoded name: Group A (control group) and Group B (study group).
入排标准
- 年龄范围
- 4 Years 至 14 Years（Child）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Pediatric patients with ORSI according to Rome III criteria
- •Contrast enema suggestive of fecal loading
- •the absence of anatomic, physiologic or pathologic reason for their constipation
排除标准
- •radiological suspicion of Hirschsprung's disease,
- •anorectal malformation,
- •mechanical obstruction,
- •failed to comply with the offered treatment (mainly if cramping abdominal pain or vomiting occurred),
- •Required bowel surgery.
- •spina bifida, spinal cord injury,
结局指标
主要结局
starting dose
时间窗: starting dose was assessed at day 180.
the effective starting dose at the begining of treatment.
end dose
时间窗: end dose was assessed at day 180.
the effective ending dose (maintenance dose) at the end of treatment.
time till not soiling
时间窗: time till not soiling was assessed at day 180.
Stool soiling (encopresis) happens in children who are toilet trained. It's when they accidentally leak feces (poop) into their underwear. Constipation is one of many causes of stool soiling. Other causes include irritable bowel syndrome or when a child is fearful of the bathroom.
次要结局
未报告次要终点
研究者
Mohammed E. Ali, Ph. D Candidate.
Assistant Lecturer
South Valley University