Comparison of the effect of 2% Atorvastatin gel on clinical symptoms of knee osteoarthritis

Not Applicable

• Conditions: Knee Osteoarthritis.

• Registration Number: IRCT20150706023084N6
• Lead Sponsor: Islamic Azad University

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 7 September 2020

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 40

Inclusion Criteria

Diagnosis of mild to moderate knee osteoarthritis by a rheumatologist based on cilinical symptoms and knee X-ray
No other topical treatments usage at least tow weeks before the study
No oral Atorvastatin usage
No other systemic analgesics or anti-inflammatory usage at least tow weeks before the study
Obtaining informed consent from the patients
patients aged between 40 and 75 years old

Exclusion Criteria

Those who need to use other oral or intravenous analgesics
Unwilling to continue or to participate in the study any further
Patients with other knee joint disorders: ( Rhumatoid Arthrities, Gout, Pseudo Gout, Infected Arthrities )
Knee corticosteroid injection in the past 3 months
Joint replacement
Pregnancy and lactation
Sensitivity to study drugs

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Pain. Timepoint: At the beginning of the study,4weeks,8weeks,12weeks after treatment. Method of measurement: WOMAC Questionnaire.;Stiffness. Timepoint: At the beginning of the study,4weeks,8weeks,12weeks after treatment. Method of measurement: WOMAC Questionnaire.;Physical Function. Timepoint: At the beginning of the study,4weeks,8weeks,12weeks after treatment. Method of measurement: WOMAC Questionnaire.