Effect of Superficial Cervical Plexus Block on the Postoperative Quality of Recovery

Not Applicable

Completed

• Conditions: Cervical Disc Prolapse
• Interventions: Other: Superficial cervical plexus block for experimental group

• Registration Number: NCT01662219
• Lead Sponsor: University Health Network, Toronto

Brief Summary

Pain and discomfort after anterior cervical spine surgery is difficult to quantify and quoted as moderate in severity, often needing oral opioid analgesics. In addition, these patients are more prone for postoperative respiratory complication due to airway edema secondary to surgical retraction or wound hematoma. Opioid analgesics provide good pain control but postoperative nausea and vomiting and respiratory depression are undesirable in these patients who are at risk for postoperative wound hematoma and airway edema The use of multimodal analgesia is rapidly becoming the 'standard of care' for preventing pain after ambulatory procedures at most surgery centers throughout the world . The purpose of this study is to determine whether superficial cervical plexus block will improve the postoperative quality of recovery as measured by Quality of Recovery 40 questionnaire (QoR-40) in patients undergoing elective anterior cervical discectomy and fusion.

Detailed Description

Anterior cervical discectomy and fusion is increasingly being done as a day surgery or short stay surgery. Postoperative pain is the leading cause of unplanned hospital admissions following day surgery, a major source of dissatisfaction and often impairs the quality of recovery. Opioid analgesics alone are not always effective and may also worsen the postoperative nausea and vomiting and in turn the postoperative recovery. This study is designed to find out if an injection of freezing on the side of neck around the nerves (superficial cervical plexus block) improves the quality of recovery from anesthesia and surgery by reducing the pain, analgesic consumption after anterior cervical spine surgery.

Primary Outcome Measure The primary outcome measure is the global QoR-40 aggregate score at 24 hours after surgery.

Secondary Outcome Measures

* Postoperative pain scores (first 24 hours)

* Total analgesic consumption (first 24 hours)

* Time for first opioid administration

* Postop Nausea and vomiting (first 24 hours)

* Post operative sedation (first 24 hours)

Study Timeline

• Study First Submitted: 2012-07-24
• Study Start: 2012-08
• Study First Submitted QC: 2012-08-07
• Study First Posted: 2012-08-10
• Primary Completion: 2014-06
• Study Completion: 2014-06
• Status Verified: 2018-02
• Last Update Submitted: 2018-02-05
• Last Update Posted: 2018-02-06

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 46

Inclusion Criteria

• all adult patients
• aged 18-80 years
• with ASA class I - III
• undergoing anterior cervical disc surgery in supine position

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Exclusion Criteria

1. In patients who are allergic to local anesthetics
2. ASA- IV patients
3. Lack of informed consent
4. Pregnant patient

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Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
superficial cervical plexus block	Superficial cervical plexus block for experimental group	superficial cervical plexus block for experimental group

Primary Outcome Measures

Name	Time	Method
The primary outcome measure is the global QoR-40 aggregate score after ACDF surgery.	24 hours

Secondary Outcome Measures

Name	Time	Method
Post operative analgesic consumption	24 hours
post operative nausea and vomiting	24 hrs
post operative sedation score	24 hrs
time for the first dose of opioid consumption	24 hrs
post operative pain score assessment	24 hours

Trial Locations

Locations (1)

Toronto Western Hospital,UHN.; 🇨🇦 Toronto, Ontario, Canada