A Randomized Controlled Trial to compare the conventional and revised anatomical landmarks for ultrasound guided cooled radiofrequency ablation of genicular nerves in patients with chronic knee osteoarthritis
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 90
- 试验地点
- 1
- 主要终点
- Difference in the median Oxford Knee Score
研究概览
简要总结
Knee osteoarthritis is one of the most common degenerative conditions in the elderly age group. The definitive treatment is knee replacement surgery, but most of the patients will not be fit for surgery. Minimally invasive procedures like radiofrequency ablation of genicular nerves around the knee joint is a successful alternative for surgery. Cooled Radiofrequency ablation is a new modality that effectively ablates the genicular nerves. Previously it was done under fluoroscopy guidance but ultrasound guidance has better advantages of being radiation free and accurate capturing of nerves. Previous landmarks that have been used for ultrasound guided ablation did not cover the entire nerves, thus providing less pain relief. Recently developed revised anatomical landmarks effectively block the genicular nerves and provide better pain relief than conventional technique.
研究设计
- 研究类型
- Interventional
- 分配方式
- Computer generated randomization
- 盲法
- Participant and Outcome Assessor Blinded
入排标准
- 年龄范围
- 40.00 Year(s) 至 80.00 Year(s)(—)
- 性别
- All
入选标准
- •Patients with symptomatic knee osteoarthritis graded II,III&IV according to the Kellgren-Lawrence system.
排除标准
- •Pain and functional limitations due to rheumatoid arthritis, gout and psoriatic arthritis.
- •Active infection of knee joint
- •Patients receiving any other invasive treatment for knee osteoarthritis.
结局指标
主要结局
Difference in the median Oxford Knee Score
时间窗: after 1, 4 and 12 weeks
次要结局
- Median Numerical Rating Scale (NRS)(after 1, 4 and 12 weeks)
- Proportion of patients developing skin burns, hematoma and numbness(immediately and within 1 week)
